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FlyAtlas: the Drosophila gene expression atlas

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Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.


This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)


Searching for FBGN0033742 through 18771 annotations produced 1 hits



(CG8550):

Annotation Number : CG8550
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0033742
Gbrowse : chr2R:8359419-8361321 (+) // 100.0 //
Probeset : 1636258_at
Accessions : protein= NP_610787;, nucleotide= NM_136943;
Interpro : 0004222 // metalloendopeptidase activity // inferred from sequence or structural similarity /// 0004222 // metalloendope
FlyMine data for FBgn0033742.
Homophila reports that CG8550 is a close match (7e-11) to human gene ECE1 (NP_001388), a gene associated with Hirschsprung disease, cardiac defects, and autonomic dysfunction (3);{Hypertension, essential, susceptibility to}, 145500 (3).
VDRC has 2 RNAi stocks for FBgn0033742 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain1 ± 00 of 4 0.10Down
Head61 ± 54 of 4 5.20Up
Eye23 ± 24 of 4 1.97Up
Thoracicoabdominal ganglion5 ± 10 of 4 0.50Down
Salivary gland21 ± 20 of 4 1.83Up
Crop6 ± 31 of 4 0.50None
Midgut8 ± 10 of 4 0.70None
Tubule4 ± 00 of 4 0.40Down
Hindgut11 ± 30 of 4 1.00None
Heart43 ± 24 of 4 3.65Up
Fat body107 ± 284 of 4 9.12Up
Ovary1 ± 00 of 4 0.10Down
Testis9 ± 01 of 4 0.80None
Male accessory glands7 ± 20 of 4 0.60None
Virgin spermatheca85 ± 34 of 4 7.26Up
Mated spermatheca63 ± 24 of 4 5.36Up
Adult carcass71 ± 24 of 4 6.10Up
Larval CNS3 ± 20 of 4 0.32Down
Larval Salivary gland17 ± 14 of 4 1.44Up
Larval midgut6 ± 20 of 4 0.58None
Larval tubule7 ± 20 of 4 0.60None
Larval hindgut8 ± 12 of 4 0.72None
Larval fat body278 ± 324 of 423.50Up
Larval trachea3 ± 21 of 4 0.27Down
Larval carcass3 ± 10 of 4 0.32Down
S2 cells (growing)3 ± 10 of 4 0.30Down
Whole fly11 ± 14 of 4

Looking for FBgn0033742. 1 entries matched from 18771, in 1 s.


Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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