FlyAtlas: the Drosophila gene expression atlas

Biotechnology & Biological Sciences Research Council

Home & Search

Batch/table Search

Tissues Search

BLASTP Search

About & FAQ

Top 50

Original data

Interesting meta-analysis

Links

Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

Searching for FBGN0033979 through 18771 annotations produced 1 hits

Cyp6a19 (Cyp6a19):

Annotation Number : CG10243
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0033979
Gbrowse : chr2R:10765292-10767260 (+) // 100.0 //
Probeset : 1639381_at
Accessions : protein= NP_611001;, nucleotide= NM_137157;
Pathway : 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane //
Interpro : 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred fro
FlyMine data for FBgn0033979.
BDGP gene expression has embryonic in situ data for Cyp6a19: 4 pix of staining in 1 body parts.
Homophila reports that CG10243 is a close match (2e-11) to human gene CPD6;CYP2D6;P450DB1 (NP_001020332), a gene associated with Codeine sensitivity (3);Debrisoquine sensitivity (3);{?Parkinsonism, susceptibility to} (1).
BioGrid reports that CG10243 interacts with CG6950 CG8694 .
VDRC has 3 RNAi stocks for FBgn0033979 available for purchase.

Tissue	mRNA Signal	Present Call	Enrichment	Affy Call
Brain	6 ± 0	2 of 4	0.00	Down
Head	12 ± 0	4 of 4	0.00	Down
Eye	11 ± 2	4 of 4	0.01	Down
Thoracicoabdominal ganglion	11 ± 1	3 of 4	0.00	Down
Salivary gland	27 ± 2	4 of 4	0.03	Down
Crop	24 ± 4	4 of 4	0.00	Down
Midgut	26 ± 2	4 of 4	0.00	Down
Tubule	47 ± 10	4 of 4	0.10	Down
Hindgut	27 ± 1	4 of 4	0.00	Down
Heart	13 ± 1	4 of 4	0.02	Down
Fat body	28 ± 7	4 of 4	0.04	Down
Ovary	1656 ± 20	4 of 4	2.00	Up
Testis	6 ± 1	2 of 4	0.00	Down
Male accessory glands	12 ± 2	2 of 4	0.00	Down
Virgin spermatheca	35 ± 4	4 of 4	0.04	Down
Mated spermatheca	21 ± 3	4 of 4	0.03	Down
Adult carcass	33 ± 7	4 of 4	0.00	Down
Larval CNS	6 ± 2	4 of 4	0.01	Down
Larval Salivary gland	14 ± 1	3 of 4	0.02	Down
Larval midgut	20 ± 2	4 of 4	0.03	Down
Larval tubule	16 ± 2	3 of 4	0.00	Down
Larval hindgut	21 ± 3	4 of 4	0.03	Down
Larval fat body	14 ± 2	1 of 4	0.00	Down
Larval trachea	12 ± 5	3 of 4	0.02	Down
Larval carcass	10 ± 2	2 of 4	0.01	Down
S2 cells (growing)	7 ± 0	3 of 4	0.01	Down
Whole fly	816 ± 37	4 of 4

Looking for FBgn0033979. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720