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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0034070 through 18771 annotations produced 1 hits

agrin-like (SP2353):

Annotation Number : CG8403
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0034070
Gbrowse : chr2R:11919464-11933442 (+) // 100.0 //
Probeset : 1625982_at
Accessions : protein= NP_611082;, nucleotide= NM_137238;
FlyMine data for FBgn0034070.
Homophila reports that CG8403 is a close match (1e-11) to human gene CRB1;LCA8;RP12 (NP_957705), a gene associated with Leber congenital amaurosis VIII (3);Pigmented paravenous chorioretinal atrophy, 172870 (3);Retinitis pigmentosa-12, autosomal recessive, 600105 (3).
VDRC has 2 RNAi stocks for FBgn0034070 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain148 64 of 412.70Up
Head58 54 of 4 5.00Up
Eye52 54 of 4 4.46Up
Thoracicoabdominal ganglion105 94 of 4 9.00Up
Salivary gland21 31 of 4 1.85None
Crop9 11 of 4 0.80None
Midgut5 11 of 4 0.40Down
Tubule6 00 of 4 0.50Down
Hindgut8 10 of 4 0.80None
Heart6 10 of 4 0.56Down
Fat body12 73 of 4 1.06None
Ovary2 00 of 4 0.20Down
Testis5 10 of 4 0.40Down
Male accessory glands8 10 of 4 0.70None
Virgin spermatheca12 11 of 4 1.10None
Mated spermatheca19 82 of 4 1.64None
Adult carcass24 13 of 4 2.10Up
Larval CNS87 74 of 4 7.47Up
Larval Salivary gland6 00 of 4 0.58Down
Larval midgut5 20 of 4 0.48None
Larval tubule5 10 of 4 0.50Down
Larval hindgut6 30 of 4 0.54None
Larval fat body5 10 of 4 0.40Down
Larval trachea9 51 of 4 0.79None
Larval carcass9 20 of 4 0.82None
S2 cells (growing)3 10 of 4 0.33Down
Whole fly11 12 of 4

Looking for FBgn0034070. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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