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FlyAtlas: the Drosophila gene expression atlas

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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.


This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)


Searching for FBGN0035049 through 18771 annotations produced 3 hits



Matrix metalloproteinase 1 (Mmp1):

Annotation Number : CG4859
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0035049
Gbrowse : chr2R:20562188-20574897 (-) // 100.0 //
Probeset : 1632204_at
Accessions : protein= NP_523852; /// NP_726473;, nucleotide= NM_079128; /// NM_166683;
Pathway : open tracheal system // inferred from mutant phenotype /// 0035071 // salivary gland cell autophagic cell death // infe
Interpro : open tracheal system // inferred from mutant phenotype /// 0048102 // autophagic cell death // inferred from expression
FlyMine data for FBgn0035049.
BDGP gene expression has embryonic in situ data for Mmp1: 19 pix of staining in 4 body parts.
Homophila reports that CG4859 is a close match (2e-11) to human gene CACP;HAPO;MSF;PRG4;SZP (NP_005798), a gene associated with Camptodactyly-arthropathy-coxa vara-pericarditis syndrome, 208250 (3).
BioGrid reports that CG4859 interacts with CG6281 CG1794 .
TRiP has 1 RNAi stocks for FBgn0035049 available for purchase.
VDRC has 1 RNAi stocks for FBgn0035049 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain12 ± 14 of 4 0.70None
Head46 ± 34 of 4 2.80Up
Eye22 ± 14 of 4 1.33None
Thoracicoabdominal ganglion14 ± 24 of 4 0.90None
Salivary gland16 ± 22 of 4 0.97None
Crop14 ± 04 of 4 0.90None
Midgut31 ± 34 of 4 1.90Up
Tubule28 ± 34 of 4 1.70Up
Hindgut39 ± 44 of 4 2.40Up
Heart11 ± 04 of 4 0.71None
Fat body14 ± 04 of 4 0.87None
Ovary4 ± 02 of 4 0.20Down
Testis31 ± 34 of 4 1.90Up
Male accessory glands10 ± 42 of 4 0.60None
Virgin spermatheca12 ± 14 of 4 0.77None
Mated spermatheca22 ± 34 of 4 1.36None
Adult carcass65 ± 44 of 4 3.90Up
Larval CNS12 ± 14 of 4 0.72None
Larval Salivary gland15 ± 52 of 4 0.93None
Larval midgut28 ± 64 of 4 1.70None
Larval tubule60 ± 54 of 4 3.60Up
Larval hindgut27 ± 34 of 4 1.68Up
Larval fat body59 ± 64 of 4 3.60Up
Larval trachea60 ± 204 of 4 3.64Up
Larval carcass61 ± 174 of 4 3.70None
S2 cells (growing)94 ± 114 of 4 5.68Up
Whole fly16 ± 24 of 4



Matrix metalloproteinase 1 (Mmp1):

Annotation Number : CG4859
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0035049
Gbrowse : chr2R:20558816-20574897 (-) // 100.0 //
Probeset : 1623160_at
Accessions : protein= NP_523852; /// NP_726473;, nucleotide= NM_079128; /// NM_166683;
Pathway : open tracheal system // inferred from mutant phenotype /// 0035071 // salivary gland cell autophagic cell death // infe
Interpro : open tracheal system // inferred from mutant phenotype /// 0048102 // autophagic cell death // inferred from expression
FlyMine data for FBgn0035049.
BDGP gene expression has embryonic in situ data for Mmp1: 19 pix of staining in 4 body parts.
Homophila reports that CG4859 is a close match (2e-11) to human gene CACP;HAPO;MSF;PRG4;SZP (NP_005798), a gene associated with Camptodactyly-arthropathy-coxa vara-pericarditis syndrome, 208250 (3).
BioGrid reports that CG4859 interacts with CG6281 CG1794 .
TRiP has 1 RNAi stocks for FBgn0035049 available for purchase.
VDRC has 1 RNAi stocks for FBgn0035049 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain46 ± 104 of 4 0.60Down
Head118 ± 114 of 4 1.50Up
Eye19 ± 04 of 4 0.25Down
Thoracicoabdominal ganglion84 ± 24 of 4 1.10None
Salivary gland38 ± 14 of 4 0.48Down
Crop79 ± 94 of 4 1.00None
Midgut400 ± 124 of 4 5.00Up
Tubule308 ± 174 of 4 3.80Up
Hindgut403 ± 434 of 4 5.00Up
Heart27 ± 54 of 4 0.34Down
Fat body49 ± 64 of 4 0.61Down
Ovary5 ± 13 of 4 0.10Down
Testis28 ± 24 of 4 0.30Down
Male accessory glands22 ± 103 of 4 0.30Down
Virgin spermatheca49 ± 94 of 4 0.61Down
Mated spermatheca62 ± 64 of 4 0.78None
Adult carcass99 ± 64 of 4 1.20None
Larval CNS57 ± 74 of 4 0.71Down
Larval Salivary gland47 ± 154 of 4 0.59None
Larval midgut578 ± 184 of 4 7.18Up
Larval tubule886 ± 654 of 411.00Up
Larval hindgut446 ± 154 of 4 5.55Up
Larval fat body166 ± 274 of 4 2.10Up
Larval trachea134 ± 304 of 4 1.67Up
Larval carcass331 ± 524 of 4 4.12Up
S2 cells (growing)787 ± 834 of 4 9.78Up
Whole fly80 ± 74 of 4



Matrix metalloproteinase 1 (Mmp1):

Annotation Number : CG4859
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0035049
Gbrowse : chr2R:20562188-20574897 (-) // 100.0 //
Probeset : 1625761_a_at
Accessions : protein= NP_523852; /// NP_726473;, nucleotide= NM_079128; /// NM_166683;
Pathway : open tracheal system // inferred from mutant phenotype /// 0035071 // salivary gland cell autophagic cell death // infe
Interpro : open tracheal system // inferred from mutant phenotype /// 0048102 // autophagic cell death // inferred from expression
FlyMine data for FBgn0035049.
BDGP gene expression has embryonic in situ data for Mmp1: 19 pix of staining in 4 body parts.
Homophila reports that CG4859 is a close match (2e-11) to human gene CACP;HAPO;MSF;PRG4;SZP (NP_005798), a gene associated with Camptodactyly-arthropathy-coxa vara-pericarditis syndrome, 208250 (3).
BioGrid reports that CG4859 interacts with CG6281 CG1794 .
TRiP has 1 RNAi stocks for FBgn0035049 available for purchase.
VDRC has 1 RNAi stocks for FBgn0035049 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain19 ± 10 of 4 0.70Down
Head52 ± 34 of 4 1.80Up
Eye17 ± 13 of 4 0.60Down
Thoracicoabdominal ganglion28 ± 12 of 4 1.00None
Salivary gland34 ± 20 of 4 1.18None
Crop21 ± 21 of 4 0.70None
Midgut107 ± 74 of 4 3.70Up
Tubule58 ± 34 of 4 2.00Up
Hindgut100 ± 54 of 4 3.40Up
Heart15 ± 14 of 4 0.52Down
Fat body15 ± 30 of 4 0.53Down
Ovary3 ± 10 of 4 0.10Down
Testis18 ± 10 of 4 0.60Down
Male accessory glands16 ± 50 of 4 0.60None
Virgin spermatheca9 ± 20 of 4 0.34Down
Mated spermatheca12 ± 20 of 4 0.44Down
Adult carcass58 ± 84 of 4 2.00Up
Larval CNS13 ± 20 of 4 0.45Down
Larval Salivary gland19 ± 40 of 4 0.67None
Larval midgut101 ± 24 of 4 3.50Up
Larval tubule229 ± 54 of 4 7.90Up
Larval hindgut81 ± 34 of 4 2.80Up
Larval fat body47 ± 61 of 4 1.60None
Larval trachea81 ± 294 of 4 2.82Up
Larval carcass72 ± 262 of 4 2.50None
S2 cells (growing)473 ± 294 of 416.29Up
Whole fly29 ± 10 of 4

Looking for FBgn0035049. 3 entries matched from 18771, in 1 s.


Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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