FlyAtlas: the Drosophila gene expression atlas

Biotechnology & Biological Sciences Research Council

Home & Search

Batch/table Search

Tissues Search

BLASTP Search

About & FAQ

Top 50

Original data

Interesting meta-analysis

Links

Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

Searching for FBGN0035298 through 18771 annotations produced 1 hits

citric acid synthetase (CG1140):

Annotation Number : CG1140
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0035298
Gbrowse : chr3L:1963142-1966808 (+) // 100.0 //
Probeset : 1629939_a_at
Accessions : protein= NP_647683; /// NP_728699;, nucleotide= NM_139426; /// NM_167928;
Pathway : 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from seq
Interpro : 0008260 // 3-oxoacid CoA-transferase activity // inferred from sequence or structural similarity /// 0008260 // 3-oxoaci
FlyMine data for FBgn0035298.
BDGP gene expression has embryonic in situ data for CG1140: 16 pix of staining in 11 body parts.
Homophila reports that CG1140 is a close match (2e-174) to human gene OXCT1;OXCT;SCOT (NP_000427), a gene associated with Succinyl CoA:3-oxoacid CoA transferase deficiency, 245050 (3).
BioGrid reports that CG1140 interacts with CG13045 .
VDRC has 2 RNAi stocks for FBgn0035298 available for purchase.

Tissue	mRNA Signal	Present Call	Enrichment	Affy Call
Brain	58 ± 3	4 of 4	0.30	Down
Head	185 ± 9	4 of 4	1.00	None
Eye	115 ± 9	4 of 4	0.63	Down
Thoracicoabdominal ganglion	60 ± 4	4 of 4	0.30	Down
Salivary gland	93 ± 9	4 of 4	0.51	Down
Crop	152 ± 7	4 of 4	0.80	Down
Midgut	172 ± 4	4 of 4	0.90	None
Tubule	1729 ± 129	4 of 4	9.50	Up
Hindgut	496 ± 19	4 of 4	2.70	Up
Heart	400 ± 18	4 of 4	2.19	Up
Fat body	472 ± 52	4 of 4	2.59	Up
Ovary	108 ± 3	4 of 4	0.60	Down
Testis	24 ± 2	4 of 4	0.10	Down
Male accessory glands	61 ± 8	4 of 4	0.30	Down
Virgin spermatheca	373 ± 3	4 of 4	2.05	Up
Mated spermatheca	204 ± 14	4 of 4	1.12	None
Adult carcass	391 ± 18	4 of 4	2.10	Up
Larval CNS	100 ± 11	4 of 4	0.55	Down
Larval Salivary gland	190 ± 8	4 of 4	1.04	None
Larval midgut	193 ± 7	4 of 4	1.06	None
Larval tubule	266 ± 45	4 of 4	1.50	None
Larval hindgut	758 ± 50	4 of 4	4.16	Up
Larval fat body	43 ± 4	4 of 4	0.20	Down
Larval trachea	187 ± 15	4 of 4	1.03	None
Larval carcass	364 ± 57	4 of 4	2.00	None
S2 cells (growing)	103 ± 9	4 of 4	0.57	Down
Whole fly	182 ± 6	4 of 4

Looking for FBgn0035298. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720