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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0036222 through 18771 annotations produced 1 hits

Succinate dehydrogenase Flavoprotein subunit (CG5718):

Annotation Number : CG5718
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0036222
Gbrowse : chr3L:11915709-11917857 (-) // 99.68 //
Probeset : 1641313_at
Accessions : protein= NP_648523;, nucleotide= NM_140266;
Pathway : 0005749 // mitochondrial respiratory chain complex II // inferred from sequence or structural similarity
Interpro : "0008177 // succinate dehydrogenase (ubiquinone) activity // inferred from sequence or structural similarity /// 0008177
FlyMine data for FBgn0036222.
BDGP gene expression has embryonic in situ data for CG5718: 2 pix of staining in 1 body parts.
Homophila reports that CG5718 is a close match (0) to human gene SDHA;SDH2;SDHF (NP_004159), a gene associated with Leigh syndrome, 256000 (3);Mitochondrial respiratory chain complex II deficiency, 252011 (3).
VDRC has 3 RNAi stocks for FBgn0036222 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain5 11 of 4 0.20Down
Head3 00 of 4 0.10Down
Eye1 00 of 4 0.04Down
Thoracicoabdominal ganglion2 10 of 4 0.10Down
Salivary gland21 41 of 4 0.64None
Crop7 21 of 4 0.20Down
Midgut5 10 of 4 0.20Down
Tubule7 00 of 4 0.20Down
Hindgut7 10 of 4 0.20Down
Heart3 10 of 4 0.09Down
Fat body7 40 of 4 0.22Down
Ovary0 00 of 4 0.00Down
Testis460 184 of 413.50Up
Male accessory glands11 31 of 4 0.30Down
Virgin spermatheca6 20 of 4 0.20Down
Mated spermatheca12 32 of 4 0.37Down
Adult carcass5 10 of 4 0.20Down
Larval CNS5 31 of 4 0.17Down
Larval Salivary gland10 11 of 4 0.29Down
Larval midgut3 10 of 4 0.10Down
Larval tubule6 10 of 4 0.20Down
Larval hindgut4 10 of 4 0.14Down
Larval fat body44 194 of 4 1.30None
Larval trachea1 10 of 4 0.05Down
Larval carcass6 10 of 4 0.19Down
S2 cells (growing)3 10 of 4 0.10Down
Whole fly34 24 of 4

Looking for FBgn0036222. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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