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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0036491 through 18771 annotations produced 1 hits

Bestrophin 4 (Best4):

Annotation Number : CG7259
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0036491
Gbrowse : chr3L:15292400-15293992 (+) // 100.0 //
Probeset : 1626941_at
Accessions : protein= NP_001097609;, nucleotide= NM_001104139;
FlyMine data for FBgn0036491.
Homophila reports that CG7259 is a close match (8e-77) to human gene ARB;BEST1;VMD2 (NP_004174), a gene associated with Bestrophinopathy, 611809 (3);Macular dystrophy, vitelliform type, 153700 (3);Maculopathy, bull's-eye, 153870 (3);Vitelliform macular dystrophy, adult-onset, 608161 (3).
TRiP has 1 RNAi stocks for FBgn0036491 available for purchase.
VDRC has 3 RNAi stocks for FBgn0036491 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain2 00 of 4 0.20Down
Head3 10 of 4 0.30Down
Eye0 00 of 4 0.07Down
Thoracicoabdominal ganglion4 10 of 4 0.40Down
Salivary gland11 60 of 4 0.99None
Crop4 10 of 4 0.40Down
Midgut7 30 of 4 0.70None
Tubule4 00 of 4 0.40Down
Hindgut6 00 of 4 0.50Down
Heart3 20 of 4 0.33Down
Fat body10 21 of 4 0.90None
Ovary4 00 of 4 0.40Down
Testis128 54 of 411.30Up
Male accessory glands9 50 of 4 0.90None
Virgin spermatheca8 10 of 4 0.76None
Mated spermatheca7 10 of 4 0.64None
Adult carcass10 10 of 4 1.00None
Larval CNS5 10 of 4 0.44Down
Larval Salivary gland5 10 of 4 0.46Down
Larval midgut12 11 of 4 1.09None
Larval tubule6 00 of 4 0.50Down
Larval hindgut7 11 of 4 0.70None
Larval fat body23 82 of 4 2.10None
Larval trachea4 31 of 4 0.39Down
Larval carcass6 10 of 4 0.58None
S2 cells (growing)42 34 of 4 3.73Up
Whole fly11 13 of 4

Looking for FBgn0036491. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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