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FlyAtlas: the Drosophila gene expression atlas

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Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.


This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)


Searching for FBGN0037709 through 18771 annotations produced 1 hits



(CG8199):

Annotation Number : CG8199
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0037709
Gbrowse : chr3R:5381516-5383509 (+) // 100.0 //
Probeset : 1637547_at
Accessions : protein= NP_649905;, nucleotide= NM_141648;
Pathway : 0017086 // 3-methyl-2-oxobutanoate dehydrogenase (lipoamide) complex // inferred from sequence or structural similarity
Interpro : "0003863 // 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity // inferred from sequence or
FlyMine data for FBgn0037709.
BDGP gene expression has embryonic in situ data for CG8199: 2 pix of staining in 1 body parts.
Homophila reports that CG8199 is a close match (3e-22) to human gene PDHA1;PHE1A (NP_000275), a gene associated with Leigh syndrome, X-linked, 308930 (3);Pyruvate dehydrogenase deficiency, 312170 (3).
VDRC has 2 RNAi stocks for FBgn0037709 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain27 ± 24 of 4 0.20Down
Head127 ± 34 of 4 1.10None
Eye74 ± 74 of 4 0.63Down
Thoracicoabdominal ganglion35 ± 24 of 4 0.30Down
Salivary gland122 ± 94 of 4 1.04None
Crop126 ± 54 of 4 1.10None
Midgut100 ± 44 of 4 0.90None
Tubule631 ± 434 of 4 5.40Up
Hindgut118 ± 54 of 4 1.00None
Heart263 ± 94 of 4 2.25Up
Fat body317 ± 384 of 4 2.70Up
Ovary150 ± 54 of 4 1.30Up
Testis17 ± 24 of 4 0.20Down
Male accessory glands28 ± 04 of 4 0.20Down
Virgin spermatheca245 ± 94 of 4 2.09Up
Mated spermatheca212 ± 184 of 4 1.81Up
Adult carcass228 ± 104 of 4 1.90Up
Larval CNS80 ± 154 of 4 0.68Down
Larval Salivary gland208 ± 164 of 4 1.78Up
Larval midgut111 ± 74 of 4 0.95None
Larval tubule100 ± 64 of 4 0.90None
Larval hindgut300 ± 234 of 4 2.55Up
Larval fat body45 ± 34 of 4 0.40Down
Larval trachea143 ± 234 of 4 1.22None
Larval carcass174 ± 324 of 4 1.49None
S2 cells (growing)42 ± 24 of 4 0.36Down
Whole fly117 ± 104 of 4

Looking for FBgn0037709. 1 entries matched from 18771, in 1 s.


Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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