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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0038436 through 18771 annotations produced 1 hits

Guanylyl cyclase at 89Db (Gyc-89Db):

Annotation Number : CG14886
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0038436
Gbrowse : chr3R:12303092-12306794 (+) // 100.0 //
Probeset : 1624528_at
Accessions : protein= NP_650551;, nucleotide= NM_142294;
Pathway : "0005737 // cytoplasm // inferred from electronic annotation /// 0008074 // guanylate cyclase complex
Interpro : soluble // inferred from sequence or structural similarity /// 0008074 // guanylate cyclase complex
FlyMine data for FBgn0038436.
Homophila reports that CG14886 is a close match (2e-36) to human gene CORD6;GUC2D;GUCY2D;LCA1 (NP_000171), a gene associated with Cone-rod dystrophy 6, 601777(3);Leber congenital amaurosis I, 204000 (3).
BioGrid reports that CG14886 interacts with CG17666 CG4394 CG7757 CG8854 CG9572 .
TRiP has 1 RNAi stocks for FBgn0038436 available for purchase.
VDRC has 4 RNAi stocks for FBgn0038436 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain32 14 of 417.20Up
Head7 10 of 4 4.00Up
Eye2 10 of 4 1.39None
Thoracicoabdominal ganglion34 34 of 418.20Up
Salivary gland1 00 of 4 0.86None
Crop2 00 of 4 1.20None
Midgut1 00 of 4 0.50None
Tubule0 00 of 4 0.40Down
Hindgut2 10 of 4 1.30None
Heart0 00 of 4 0.26None
Fat body5 10 of 4 3.08Up
Ovary1 00 of 4 0.90None
Testis0 00 of 4 0.40None
Male accessory glands3 10 of 4 1.70None
Virgin spermatheca0 00 of 4 0.38None
Mated spermatheca2 10 of 4 1.25None
Adult carcass4 10 of 4 2.30None
Larval CNS78 104 of 441.41Up
Larval Salivary gland1 00 of 4 0.64None
Larval midgut1 00 of 4 0.71None
Larval tubule0 00 of 4 0.40None
Larval hindgut2 10 of 4 1.50None
Larval fat body2 10 of 4 1.40None
Larval trachea1 10 of 4 0.53None
Larval carcass1 00 of 4 0.58None
S2 cells (growing)0 00 of 4 0.20None
Whole fly1 10 of 4

Looking for FBgn0038436. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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