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FlyAtlas: the Drosophila gene expression atlas

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Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.


This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)


Searching for FBGN0039015 through 18771 annotations produced 1 hits



Tak1-like 2 (Takl2):

Annotation Number : CG4803
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0039015
Gbrowse : chr3R:18558329-18559547 (-) // 100.0 //
Probeset : 1632359_at
Accessions : protein= NP_651090;, nucleotide= NM_142833;
Interpro : 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred
FlyMine data for FBgn0039015.
Homophila reports that CG4803 is a close match (8e-11) to human gene MEN2A;RET (NP_066124), a gene associated with Central hypoventilation syndrome, congenital, 209880 (3);Hirschsprung disease, 142623 (3);Medullary thyroid carcinoma, 155240 (3);Multiple endocrine neoplasia IIA, 171400 (3);Multiple endocrine neoplasia IIB, 162300 (3);Pheochromocytoma, 171300 (3);Renal agenesis, 191830 (3).
VDRC has 2 RNAi stocks for FBgn0039015 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain4 ± 00 of 4 0.20Down
Head7 ± 00 of 4 0.20Down
Eye4 ± 10 of 4 0.17Down
Thoracicoabdominal ganglion4 ± 10 of 4 0.10Down
Salivary gland5 ± 20 of 4 0.19Down
Crop5 ± 20 of 4 0.20Down
Midgut335 ± 104 of 411.60Up
Tubule96 ± 214 of 4 3.30Up
Hindgut80 ± 54 of 4 2.80Up
Heart4 ± 10 of 4 0.15Down
Fat body9 ± 30 of 4 0.33Down
Ovary3 ± 00 of 4 0.10Down
Testis2 ± 00 of 4 0.10Down
Male accessory glands5 ± 10 of 4 0.20Down
Virgin spermatheca6 ± 20 of 4 0.22Down
Mated spermatheca4 ± 10 of 4 0.15Down
Adult carcass12 ± 30 of 4 0.40Down
Larval CNS3 ± 20 of 4 0.13Down
Larval Salivary gland3 ± 10 of 4 0.13Down
Larval midgut213 ± 74 of 4 7.36Up
Larval tubule238 ± 154 of 4 8.20Up
Larval hindgut119 ± 94 of 4 4.11Up
Larval fat body11 ± 30 of 4 0.40Down
Larval trachea5 ± 30 of 4 0.18Down
Larval carcass4 ± 10 of 4 0.15Down
S2 cells (growing)1 ± 00 of 4 0.04Down
Whole fly29 ± 34 of 4

Looking for FBgn0039015. 1 entries matched from 18771, in 1 s.


Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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