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FlyAtlas: the Drosophila gene expression atlas

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Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.


This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)


Searching for FBGN0039849 through 18771 annotations produced 2 hits



(CG11334):

Annotation Number : HDC16583
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0039849
Gbrowse : chr3R:27288311-27288836 (-) // 100.0 //
Probeset : 1640926_at
Accessions : protein= NP_651868; /// NP_733430;, nucleotide= NM_143611; /// NM_170551;
Pathway : 0005851 // eukaryotic translation initiation factor 2B complex // inferred from sequence or structural similarity
Interpro : 0045182 // translation regulator activity // inferred from sequence or structural similarity
FlyMine data for FBgn0039849.
BDGP gene expression has embryonic in situ data for CG11334: 19 pix of staining in 4 body parts.
VDRC has 3 RNAi stocks for FBgn0039849 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain0 ± 00 of 4 0.30None
Head1 ± 00 of 4 0.40None
Eye1 ± 00 of 4 0.60None
Thoracicoabdominal ganglion0 ± 00 of 4 0.30None
Salivary gland9 ± 40 of 4 3.39None
Crop1 ± 00 of 4 0.60None
Midgut1 ± 00 of 4 0.50None
Tubule1 ± 00 of 4 0.70None
Hindgut1 ± 00 of 4 0.50None
Heart1 ± 10 of 4 0.56None
Fat body2 ± 00 of 4 0.75None
Ovary2 ± 10 of 4 1.00None
Testis0 ± 00 of 4 0.30None
Male accessory glands1 ± 00 of 4 0.40None
Virgin spermatheca1 ± 00 of 4 0.52None
Mated spermatheca1 ± 00 of 4 0.58None
Adult carcass2 ± 10 of 4 0.90None
Larval CNS1 ± 10 of 4 0.49None
Larval Salivary gland2 ± 00 of 4 0.96None
Larval midgut2 ± 10 of 4 0.74None
Larval tubule3 ± 10 of 4 1.40None
Larval hindgut0 ± 00 of 4 0.24None
Larval fat body4 ± 20 of 4 1.50None
Larval trachea1 ± 10 of 4 0.64None
Larval carcass1 ± 00 of 4 0.48None
S2 cells (growing)1 ± 00 of 4 0.51None
Whole fly2 ± 10 of 4



(CG11334):

Annotation Number : CG11334
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0039849
Gbrowse : chr3R:27285545-27288730 (-) // 100.0 //
Probeset : 1624246_s_at
Accessions : protein= NP_651868; /// NP_733430;, nucleotide= NM_143611; /// NM_170551;
Pathway : 0005851 // eukaryotic translation initiation factor 2B complex // inferred from sequence or structural similarity
Interpro : 0045182 // translation regulator activity // inferred from sequence or structural similarity
FlyMine data for FBgn0039849.
BDGP gene expression has embryonic in situ data for CG11334: 19 pix of staining in 4 body parts.
Homophila reports that CG11334 is a close match (4e-15) to human gene EIF2B1;EIF2BA (NP_001405), a gene associated with Leukoencephalopathy with vanishing white matter, 603896 (3).
BioGrid reports that CG11334 interacts with CG13389 CG1871 CG6963 CG7977 .
VDRC has 3 RNAi stocks for FBgn0039849 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain55 ± 14 of 4 0.20Down
Head150 ± 144 of 4 0.60Down
Eye163 ± 44 of 4 0.67Down
Thoracicoabdominal ganglion72 ± 34 of 4 0.30Down
Salivary gland179 ± 144 of 4 0.74Down
Crop137 ± 84 of 4 0.60Down
Midgut273 ± 174 of 4 1.10None
Tubule2290 ± 1444 of 4 9.40Up
Hindgut213 ± 44 of 4 0.90Down
Heart243 ± 124 of 4 1.00None
Fat body348 ± 284 of 4 1.43Up
Ovary319 ± 44 of 4 1.30Up
Testis116 ± 44 of 4 0.50Down
Male accessory glands196 ± 104 of 4 0.80Down
Virgin spermatheca195 ± 124 of 4 0.80Down
Mated spermatheca269 ± 164 of 4 1.11None
Adult carcass274 ± 194 of 4 1.10None
Larval CNS232 ± 144 of 4 0.96None
Larval Salivary gland167 ± 154 of 4 0.69Down
Larval midgut264 ± 84 of 4 1.08None
Larval tubule1486 ± 734 of 4 6.10Up
Larval hindgut256 ± 74 of 4 1.05None
Larval fat body639 ± 444 of 4 2.60Up
Larval trachea310 ± 264 of 4 1.28Up
Larval carcass157 ± 64 of 4 0.65Down
S2 cells (growing)345 ± 184 of 4 1.42Up
Whole fly243 ± 94 of 4

Looking for FBgn0039849. 2 entries matched from 18771, in 1 s.


Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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