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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0040091 through 18771 annotations produced 1 hits

lectin-58Fg (Ugt58Fa):

Annotation Number : CG4414
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0040091
Gbrowse : chr2R:18529400-18531420 (-) // 100.0 //
Probeset : 1632070_at
Accessions : protein= NP_611694;, nucleotide= NM_137850;
Interpro : "0015020 // glucuronosyltransferase activity // inferred from sequence or structural similarity /// 0015020 // glucurono
FlyMine data for FBgn0040091.
BDGP gene expression has embryonic in situ data for Ugt58Fa: 19 pix of staining in 11 body parts.
Homophila reports that CG4414 is a close match (5e-21) to human gene GNT1;UGT1;UGT1A1 (NP_000454), a gene associated with Crigler-Najjar syndrome, type I, 218800 (3);Crigler-Najjar syndrome, type II, 606785 (3);Hyperbilirubinemia, familial transcient neonatal, 237900 (3);[Gilbert syndrome], 143500 (3).
VDRC has 1 RNAi stocks for FBgn0040091 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain53 04 of 4 1.60Up
Head46 34 of 4 1.40Up
Eye56 104 of 4 1.72None
Thoracicoabdominal ganglion44 14 of 4 1.30Up
Salivary gland18 12 of 4 0.56Down
Crop35 24 of 4 1.10None
Midgut30 12 of 4 0.90None
Tubule10 10 of 4 0.30Down
Hindgut74 34 of 4 2.30Up
Heart89 24 of 4 2.73Up
Fat body54 84 of 4 1.67Up
Ovary20 14 of 4 0.60Down
Testis18 24 of 4 0.50Down
Male accessory glands59 34 of 4 1.80Up
Virgin spermatheca32 14 of 4 0.97None
Mated spermatheca53 44 of 4 1.61Up
Adult carcass37 04 of 4 1.20None
Larval CNS51 54 of 4 1.58Up
Larval Salivary gland7 11 of 4 0.24Down
Larval midgut24 21 of 4 0.75None
Larval tubule24 04 of 4 0.70Down
Larval hindgut66 34 of 4 2.03Up
Larval fat body37 24 of 4 1.10None
Larval trachea96 64 of 4 2.95Up
Larval carcass40 34 of 4 1.22None
S2 cells (growing)809 274 of 424.63Up
Whole fly32 24 of 4

Looking for FBgn0040091. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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