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FlyAtlas: the Drosophila gene expression atlas

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Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.


This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)


Searching for FBGN0040238 through 18771 annotations produced 1 hits



Bestrophin 1 (Best1):

Annotation Number : CG6264
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0040238
Gbrowse : chr3R:5987185-5996207 (-) // 100.0 //
Probeset : 1627617_at
Accessions : protein= NP_001138033; /// NP_652603;, nucleotide= NM_001144561; /// NM_144346;
Interpro : 0005254 // chloride channel activity // non-traceable author statement
FlyMine data for FBgn0040238.
Homophila reports that CG6264 is a close match (8e-108) to human gene ARB;BEST1;VMD2 (NP_004174), a gene associated with Bestrophinopathy, 611809 (3);Macular dystrophy, vitelliform type, 153700 (3);Maculopathy, bull's-eye, 153870 (3);Vitelliform macular dystrophy, adult-onset, 608161 (3).
BioGrid reports that CG6264 interacts with CG7780 .
VDRC has 1 RNAi stocks for FBgn0040238 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain144 ± 24 of 4 0.90None
Head158 ± 94 of 4 1.00None
Eye60 ± 34 of 4 0.37Down
Thoracicoabdominal ganglion270 ± 104 of 4 1.70Up
Salivary gland133 ± 84 of 4 0.82None
Crop551 ± 154 of 4 3.40Up
Midgut79 ± 44 of 4 0.50Down
Tubule551 ± 1054 of 4 3.40Up
Hindgut644 ± 254 of 4 3.90Up
Heart148 ± 214 of 4 0.91None
Fat body90 ± 134 of 4 0.55Down
Ovary428 ± 34 of 4 2.60Up
Testis25 ± 14 of 4 0.20Down
Male accessory glands274 ± 74 of 4 1.70Up
Virgin spermatheca153 ± 94 of 4 0.94None
Mated spermatheca179 ± 114 of 4 1.10None
Adult carcass95 ± 24 of 4 0.60Down
Larval CNS65 ± 124 of 4 0.40Down
Larval Salivary gland26 ± 24 of 4 0.16Down
Larval midgut155 ± 124 of 4 0.95None
Larval tubule300 ± 184 of 4 1.80Up
Larval hindgut405 ± 214 of 4 2.48Up
Larval fat body23 ± 44 of 4 0.10Down
Larval trachea150 ± 264 of 4 0.92None
Larval carcass82 ± 44 of 4 0.50Down
S2 cells (growing)435 ± 174 of 4 2.67Up
Whole fly163 ± 104 of 4

Looking for FBgn0040238. 1 entries matched from 18771, in 0 s.


Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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