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FlyAtlas: the Drosophila gene expression atlas

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Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0040281 through 18771 annotations produced 1 hits


APP-like protein interacting protein 1 (Aplip1):

Annotation Number : CG1200
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0040281
Gbrowse : chr3L:1196320-1199341 (+) // 100.0 //
Probeset : 1629678_a_at
Accessions : protein= NP_728573; /// NP_728574;, nucleotide= NM_167856; /// NM_167857;
Pathway : 0005737 // cytoplasm // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation
Interpro : 0005078 // MAP-kinase scaffold activity // inferred from physical interaction /// 0005515 // protein binding // inferred
FlyMine data for FBgn0040281.
BDGP gene expression has embryonic in situ data for Aplip1: 30 pix of staining in 17 body parts.
Homophila reports that CG1200 is a close match (4e-43) to human gene IB1;MAPK8IP1 (NP_005447), a gene associated with {Diabetes mellitus, noninsulin-dependent}, 125853 (3).
BioGrid reports that CG1200 interacts with CG5674 CG4353 CG5680 CG5433 CG7727 .
TRiP has 1 RNAi stocks for FBgn0040281 available for purchase.
VDRC has 2 RNAi stocks for FBgn0040281 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain590 ± 754 of 415.50Up
Head180 ± 134 of 4 4.70Up
Eye102 ± 24 of 4 2.71Up
Thoracicoabdominal ganglion542 ± 144 of 414.30Up
Salivary gland6 ± 31 of 4 0.18Down
Crop4 ± 00 of 4 0.10Down
Midgut5 ± 11 of 4 0.10Down
Tubule4 ± 00 of 4 0.10Down
Hindgut3 ± 10 of 4 0.10Down
Heart3 ± 11 of 4 0.09Down
Fat body5 ± 11 of 4 0.15Down
Ovary1 ± 10 of 4 0.00Down
Testis2 ± 00 of 4 0.10Down
Male accessory glands6 ± 10 of 4 0.20Down
Virgin spermatheca3 ± 10 of 4 0.08Down
Mated spermatheca2 ± 00 of 4 0.05Down
Adult carcass17 ± 42 of 4 0.50Down
Larval CNS305 ± 314 of 4 8.04Up
Larval Salivary gland9 ± 13 of 4 0.25Down
Larval midgut4 ± 11 of 4 0.11Down
Larval tubule6 ± 21 of 4 0.20Down
Larval hindgut3 ± 10 of 4 0.10Down
Larval fat body7 ± 21 of 4 0.20Down
Larval trachea3 ± 20 of 4 0.08Down
Larval carcass5 ± 11 of 4 0.16Down
S2 cells (growing)5 ± 00 of 4 0.14Down
Whole fly38 ± 64 of 4

Looking for FBgn0040281. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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