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FlyAtlas: the Drosophila gene expression atlas

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Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.


This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)


Searching for FBGN0040319 through 18771 annotations produced 1 hits



Glutamate-cysteine ligase catalytic subunit (Gclc):

Annotation Number : CG2259
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0040319
Gbrowse : chrX:7996612-8010177 (-) // 100.0 //
Probeset : 1625362_at
Accessions : protein= NP_525005; /// NP_996373;, nucleotide= NM_080266; /// NM_206650;
Pathway : 0005634 // nucleus // inferred from direct assay /// 0017109 // glutamate-cysteine ligase complex // inferred from physi
Interpro : 0000166 // nucleotide binding // inferred from electronic annotation /// 0004357 // glutamate-cysteine ligase activity /
FlyMine data for FBgn0040319.
BDGP gene expression has embryonic in situ data for Gclc: 12 pix of staining in 4 body parts.
Homophila reports that CG2259 is a close match (0) to human gene GCLC;GLCLC (NP_001489), a gene associated with Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency, 230450 (3).
BioGrid reports that CG2259 interacts with CG4919 .
VDRC has 2 RNAi stocks for FBgn0040319 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain378 ± 44 of 4 1.00None
Head328 ± 174 of 4 0.90None
Eye276 ± 164 of 4 0.76Down
Thoracicoabdominal ganglion448 ± 84 of 4 1.20Up
Salivary gland2644 ± 1094 of 4 7.29Up
Crop383 ± 184 of 4 1.10None
Midgut1370 ± 864 of 4 3.80Up
Tubule1578 ± 514 of 4 4.30Up
Hindgut557 ± 254 of 4 1.50Up
Heart631 ± 234 of 4 1.74Up
Fat body803 ± 534 of 4 2.21Up
Ovary318 ± 64 of 4 0.90None
Testis105 ± 34 of 4 0.30Down
Male accessory glands85 ± 64 of 4 0.20Down
Virgin spermatheca378 ± 174 of 4 1.04None
Mated spermatheca360 ± 294 of 4 0.99None
Adult carcass513 ± 264 of 4 1.40Up
Larval CNS87 ± 124 of 4 0.24Down
Larval Salivary gland230 ± 194 of 4 0.63Down
Larval midgut2798 ± 564 of 4 7.71Up
Larval tubule300 ± 594 of 4 0.80None
Larval hindgut295 ± 274 of 4 0.81None
Larval fat body80 ± 34 of 4 0.20Down
Larval trachea150 ± 214 of 4 0.41Down
Larval carcass208 ± 154 of 4 0.57Down
S2 cells (growing)241 ± 54 of 4 0.67Down
Whole fly363 ± 204 of 4

Looking for FBgn0040319. 1 entries matched from 18771, in 1 s.


Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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