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FlyAtlas: the Drosophila gene expression atlas

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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.


This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)


Searching for FBGN0041630 through 18771 annotations produced 2 hits



Hexosaminidase 1 (Hexo1):

Annotation Number : CG1318
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0041630
Gbrowse : chr3L:4288641-4291211 (+) // 100.0 //
Probeset : 1632188_at
Accessions : protein= NP_523924; /// NP_728974; /// NP_728975; /// NP_728976;, nucleotide= NM_079200; /// NM_168075; /// NM_168076; /// NM_168077;
Pathway : 0005886 // plasma membrane // inferred from direct assay
Interpro : "0003824 // catalytic activity // inferred from electronic annotation /// 0004553 // hydrolase activity
FlyMine data for FBgn0041630.
BDGP gene expression has embryonic in situ data for Hexo1: 17 pix of staining in 10 body parts.
Homophila reports that CG1318 is a close match (6e-39) to human gene HEXA;TSD (NP_000511), a gene associated with GM2-gangliosidosis, several forms, 272800 (3);Tay-Sachs disease, 272800 (3);[Hex A pseudodeficiency], 272800 (3).
VDRC has 1 RNAi stocks for FBgn0041630 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain425 ± 114 of 4 1.00None
Head806 ± 934 of 4 2.00Up
Eye1942 ± 1314 of 4 4.70Up
Thoracicoabdominal ganglion727 ± 344 of 4 1.80Up
Salivary gland259 ± 104 of 4 0.63Down
Crop1628 ± 134 of 4 3.90Up
Midgut2431 ± 574 of 4 5.90Up
Tubule190 ± 94 of 4 0.50Down
Hindgut1120 ± 234 of 4 2.70Up
Heart325 ± 144 of 4 0.79Down
Fat body354 ± 344 of 4 0.86None
Ovary285 ± 64 of 4 0.70Down
Testis45 ± 34 of 4 0.10Down
Male accessory glands326 ± 84 of 4 0.80Down
Virgin spermatheca810 ± 354 of 4 1.96Up
Mated spermatheca623 ± 244 of 4 1.51Up
Adult carcass298 ± 104 of 4 0.70Down
Larval CNS393 ± 564 of 4 0.95None
Larval Salivary gland519 ± 404 of 4 1.26None
Larval midgut2653 ± 2814 of 4 6.42Up
Larval tubule338 ± 144 of 4 0.80Down
Larval hindgut1139 ± 374 of 4 2.76Up
Larval fat body944 ± 1424 of 4 2.30Up
Larval trachea1819 ± 1134 of 4 4.41Up
Larval carcass761 ± 504 of 4 1.84Up
S2 cells (growing)253 ± 84 of 4 0.61Down
Whole fly413 ± 244 of 4



Hexosaminidase 1 (Hexo1):

Annotation Number : CG1318
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0041630
Gbrowse : chr3L:4288641-4291211 (+) // 100.0 //
Probeset : 1637510_s_at
Accessions : protein= NP_523924; /// NP_728974; /// NP_728975; /// NP_728976;, nucleotide= NM_079200; /// NM_168075; /// NM_168076; /// NM_168077;
Pathway : 0005886 // plasma membrane // inferred from direct assay
Interpro : "0003824 // catalytic activity // inferred from electronic annotation /// 0004553 // hydrolase activity
FlyMine data for FBgn0041630.
BDGP gene expression has embryonic in situ data for Hexo1: 17 pix of staining in 10 body parts.
Homophila reports that CG1318 is a close match (6e-39) to human gene HEXA;TSD (NP_000511), a gene associated with GM2-gangliosidosis, several forms, 272800 (3);Tay-Sachs disease, 272800 (3);[Hex A pseudodeficiency], 272800 (3).
VDRC has 1 RNAi stocks for FBgn0041630 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain244 ± 74 of 4 1.50Up
Head354 ± 234 of 4 2.20Up
Eye936 ± 874 of 4 5.84Up
Thoracicoabdominal ganglion384 ± 144 of 4 2.40Up
Salivary gland127 ± 234 of 4 0.80None
Crop724 ± 154 of 4 4.50Up
Midgut850 ± 124 of 4 5.30Up
Tubule127 ± 54 of 4 0.80Down
Hindgut586 ± 224 of 4 3.70Up
Heart150 ± 94 of 4 0.94None
Fat body149 ± 224 of 4 0.93None
Ovary126 ± 44 of 4 0.80Down
Testis31 ± 22 of 4 0.20Down
Male accessory glands183 ± 124 of 4 1.10None
Virgin spermatheca268 ± 84 of 4 1.67Up
Mated spermatheca226 ± 124 of 4 1.41Up
Adult carcass172 ± 114 of 4 1.10None
Larval CNS165 ± 174 of 4 1.03None
Larval Salivary gland235 ± 144 of 4 1.47Up
Larval midgut868 ± 1094 of 4 5.41Up
Larval tubule149 ± 94 of 4 0.90None
Larval hindgut553 ± 194 of 4 3.45Up
Larval fat body288 ± 394 of 4 1.80Up
Larval trachea846 ± 564 of 4 5.27Up
Larval carcass530 ± 444 of 4 3.31Up
S2 cells (growing)162 ± 54 of 4 1.01None
Whole fly160 ± 84 of 4

Looking for FBgn0041630. 2 entries matched from 18771, in 1 s.


Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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