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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0042630 through 18771 annotations produced 1 hits

sox-like (Sox21b):

Annotation Number : CG32139
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0042630
Gbrowse : chr3L:14105489-14124424 (-) // 99.74 //
Probeset : 1637750_at
Accessions : protein= NP_648695;, nucleotide= NM_140438;
Pathway : 0005634 // nucleus // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from electronic
Interpro : 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription
FlyMine data for FBgn0042630.
BDGP gene expression has embryonic in situ data for Sox21b: 48 pix of staining in 9 body parts.
Homophila reports that CG32139 is a close match (4e-19) to human gene SOX18;HLTS (NP_060889), a gene associated with Hypotrichosis-lymphedema-telangiectasia syndrome, 607823 (3).
VDRC has 1 RNAi stocks for FBgn0042630 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain132 74 of 418.60Up
Head23 14 of 4 3.30Up
Eye5 21 of 4 0.79None
Thoracicoabdominal ganglion24 14 of 4 3.40Up
Salivary gland694 314 of 497.40Up
Crop15 14 of 4 2.20Up
Midgut4 00 of 4 0.70None
Tubule2 00 of 4 0.40Down
Hindgut45 24 of 4 6.40Up
Heart3 10 of 4 0.42None
Fat body7 33 of 4 1.04None
Ovary0 00 of 4 0.10Down
Testis22 24 of 4 3.20Up
Male accessory glands4 20 of 4 0.70None
Virgin spermatheca7 04 of 4 1.07None
Mated spermatheca6 01 of 4 0.88None
Adult carcass7 20 of 4 1.00None
Larval CNS59 104 of 4 8.41Up
Larval Salivary gland147 154 of 420.66Up
Larval midgut2 00 of 4 0.29None
Larval tubule2 10 of 4 0.30None
Larval hindgut158 24 of 422.22Up
Larval fat body7 22 of 4 1.10None
Larval trachea2 20 of 4 0.34None
Larval carcass14 04 of 4 2.00Up
S2 cells (growing)1 00 of 4 0.24Down
Whole fly7 13 of 4

Looking for FBgn0042630. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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