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FlyAtlas: the Drosophila gene expression atlas

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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0042711 through 18771 annotations produced 2 hits


Hexokinase (Hex-t1):

Annotation Number : CG33102
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0042711
Gbrowse : chr3R:22274800-22276273 (+) // 100.0 //
Probeset : 1636223_at
Accessions : protein= NP_788744;, nucleotide= NM_176567;
Interpro : "0000166 // nucleotide binding // inferred from electronic annotation /// 0004396 // hexokinase activity // non-traceabl
FlyMine data for FBgn0042711.
Homophila reports that CG33102 is a close match (1e-62) to human gene GCK;HHF3 (NP_277042), a gene associated with Diabetes mellitus, gestational, 125851 (3);Diabetes mellitus, noninsulin-dependent, late onset, 125853 (3);Diabetes mellitus, permanent neonatal, 606176 (3);Hyperinsulinemic hypoglycemia, familial, 3, 602485 (3);MODY, type II, 125851 (3).
VDRC has 2 RNAi stocks for FBgn0042711 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain4 ± 10 of 4 0.10Down
Head8 ± 00 of 4 0.30Down
Eye4 ± 10 of 4 0.15Down
Thoracicoabdominal ganglion4 ± 10 of 4 0.10Down
Salivary gland17 ± 50 of 4 0.52None
Crop14 ± 20 of 4 0.50Down
Midgut17 ± 30 of 4 0.50Down
Tubule9 ± 00 of 4 0.30Down
Hindgut12 ± 10 of 4 0.40Down
Heart3 ± 10 of 4 0.10Down
Fat body4 ± 20 of 4 0.13Down
Ovary7 ± 12 of 4 0.20Down
Testis283 ± 44 of 4 8.70Up
Male accessory glands17 ± 10 of 4 0.50Down
Virgin spermatheca2 ± 00 of 4 0.07Down
Mated spermatheca3 ± 20 of 4 0.11Down
Adult carcass11 ± 40 of 4 0.30Down
Larval CNS4 ± 20 of 4 0.14Down
Larval Salivary gland6 ± 30 of 4 0.21Down
Larval midgut18 ± 21 of 4 0.58Down
Larval tubule11 ± 00 of 4 0.40Down
Larval hindgut12 ± 10 of 4 0.38Down
Larval fat body44 ± 143 of 4 1.40None
Larval trachea5 ± 61 of 4 0.17Down
Larval carcass17 ± 20 of 4 0.53Down
S2 cells (growing)6 ± 10 of 4 0.19Down
Whole fly32 ± 14 of 4


Hexokinase /// Hexokinase (Hex-t1 /// Hex-t2):

Annotation Number : CG32849
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0042710
Gbrowse : chr3R:22276373-22278057 (+) // 100.0 //
Probeset : 1631442_at
Accessions : protein= NP_733151;, nucleotide= NM_170272;
Interpro : "0000166 // nucleotide binding // inferred from electronic annotation /// 0004396 // hexokinase activity // inferred fro
FlyMine data for FBgn0042710.
BDGP gene expression has embryonic in situ data for Hex-t2: 2 pix of staining in 1 body parts.
Homophila reports that CG32849 is a close match (5e-103) to human gene GCK;HHF3 (NP_277042), a gene associated with Diabetes mellitus, gestational, 125851 (3);Diabetes mellitus, noninsulin-dependent, late onset, 125853 (3);Diabetes mellitus, permanent neonatal, 606176 (3);Hyperinsulinemic hypoglycemia, familial, 3, 602485 (3);MODY, type II, 125851 (3).
VDRC has 2 RNAi stocks for FBgn0042710 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain2 ± 00 of 4 0.00Down
Head5 ± 20 of 4 0.00Down
Eye4 ± 10 of 4 0.04Down
Thoracicoabdominal ganglion1 ± 00 of 4 0.00Down
Salivary gland8 ± 10 of 4 0.08Down
Crop3 ± 10 of 4 0.00Down
Midgut5 ± 20 of 4 0.10Down
Tubule2 ± 00 of 4 0.00Down
Hindgut4 ± 10 of 4 0.00Down
Heart3 ± 10 of 4 0.03Down
Fat body4 ± 20 of 4 0.04Down
Ovary2 ± 00 of 4 0.00Down
Testis1342 ± 454 of 412.60Up
Male accessory glands15 ± 10 of 4 0.10Down
Virgin spermatheca2 ± 00 of 4 0.02Down
Mated spermatheca6 ± 10 of 4 0.06Down
Adult carcass8 ± 21 of 4 0.10Down
Larval CNS2 ± 10 of 4 0.02Down
Larval Salivary gland5 ± 10 of 4 0.05Down
Larval midgut8 ± 20 of 4 0.08Down
Larval tubule6 ± 01 of 4 0.10Down
Larval hindgut6 ± 00 of 4 0.06Down
Larval fat body81 ± 423 of 4 0.80None
Larval trachea5 ± 52 of 4 0.05Down
Larval carcass3 ± 10 of 4 0.03Down
S2 cells (growing)2 ± 00 of 4 0.02Down
Whole fly106 ± 44 of 4

Looking for FBgn0042711. 2 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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