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FlyAtlas: the Drosophila gene expression atlas

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Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.


This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)


Searching for FBGN0046114 through 18771 annotations produced 1 hits



Glutamate-cysteine ligase modifier subunit (Gclm):

Annotation Number : CG4919
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID :
Gbrowse : chr3R:18510727-18512249 (-) // 100.0 //
Probeset : 1640552_at
Accessions : protein= NP_732780;, nucleotide= NM_170034;
Pathway : 0005829 // cytosol // inferred from direct assay /// 0017109 // glutamate-cysteine ligase complex // inferred from physi
Interpro : 0004357 // glutamate-cysteine ligase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activ
Homophila reports that CG4919 is a close match (2e-25) to human gene GCLM;GLCLR (NP_002052), a gene associated with {Myocardial infarction, susceptibility to} (3).
BioGrid reports that CG4919 interacts with CG5352 CG2259 .


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain43 ± 34 of 4 1.00None
Head109 ± 64 of 4 2.50Up
Eye111 ± 274 of 4 2.58None
Thoracicoabdominal ganglion92 ± 24 of 4 2.10Up
Salivary gland52 ± 73 of 4 1.21None
Crop90 ± 44 of 4 2.10Up
Midgut61 ± 34 of 4 1.40Up
Tubule380 ± 804 of 4 8.80Up
Hindgut62 ± 64 of 4 1.40None
Heart113 ± 94 of 4 2.64Up
Fat body123 ± 144 of 4 2.87Up
Ovary26 ± 53 of 4 0.60None
Testis15 ± 23 of 4 0.40Down
Male accessory glands30 ± 13 of 4 0.70None
Virgin spermatheca191 ± 94 of 4 4.44Up
Mated spermatheca212 ± 134 of 4 4.92Up
Adult carcass103 ± 64 of 4 2.40Up
Larval CNS28 ± 134 of 4 0.67None
Larval Salivary gland24 ± 54 of 4 0.56Down
Larval midgut37 ± 54 of 4 0.86None
Larval tubule35 ± 24 of 4 0.80None
Larval hindgut25 ± 23 of 4 0.59Down
Larval fat body36 ± 64 of 4 0.80None
Larval trachea19 ± 94 of 4 0.46Down
Larval carcass29 ± 42 of 4 0.69None
S2 cells (growing)18 ± 24 of 4 0.43Down
Whole fly43 ± 54 of 4

Looking for FBgn0046114. 1 entries matched from 18771, in 1 s.


Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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