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FlyAtlas: the Drosophila gene expression atlas

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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.


This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)


Searching for FBGN0050054 through 18771 annotations produced 2 hits



(CG30054):

Annotation Number : CG30054
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0050054
Gbrowse : chr2R:8511276-8512628 (+) // 100.0 //
Probeset : 1640376_a_at
Accessions : protein= NP_001036538;, nucleotide= NM_001043073;
Pathway : 0005834 // heterotrimeric G-protein complex // inferred from sequence or structural similarity
Interpro : 0000166 // nucleotide binding // inferred from electronic annotation /// 0004871 // signal transducer activity // inferr
FlyMine data for FBgn0050054.
Homophila reports that CG30054 is a close match (4e-61) to human gene AHO;GNAS;GNAS1;GPSA;PHP1A;PHP1B;POH (NP_001070956), a gene associated with Acromegaly, 102200 (3);McCune-Albright syndrome, 174800 (3);Osseous heteroplasia, progressive, 166350 (3);Pituitary ACTH secreting adenoma (3);Prolonged bleeding time, brachydac;Pseudohypoparathyroidism, type Ia, 103580 (3);Pseudohypoparathyroidism, type Ib, 603233 (3);Somatotrophinoma (3).
VDRC has 3 RNAi stocks for FBgn0050054 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain9 ± 04 of 4 2.80Up
Head3 ± 01 of 4 1.20None
Eye2 ± 10 of 4 0.63None
Thoracicoabdominal ganglion7 ± 03 of 4 2.40Up
Salivary gland10 ± 11 of 4 3.17Up
Crop4 ± 00 of 4 1.20None
Midgut5 ± 10 of 4 1.50None
Tubule3 ± 00 of 4 1.10None
Hindgut4 ± 11 of 4 1.40None
Heart2 ± 00 of 4 0.88None
Fat body5 ± 33 of 4 1.80None
Ovary2 ± 00 of 4 0.70None
Testis2 ± 01 of 4 0.90None
Male accessory glands10 ± 03 of 4 3.30Up
Virgin spermatheca2 ± 10 of 4 0.81None
Mated spermatheca4 ± 10 of 4 1.27None
Adult carcass8 ± 20 of 4 2.50None
Larval CNS5 ± 14 of 4 1.69None
Larval Salivary gland5 ± 11 of 4 1.66None
Larval midgut4 ± 10 of 4 1.46None
Larval tubule5 ± 11 of 4 1.70None
Larval hindgut1 ± 00 of 4 0.38None
Larval fat body7 ± 10 of 4 2.20None
Larval trachea1 ± 10 of 4 0.48None
Larval carcass4 ± 11 of 4 1.30None
S2 cells (growing)2 ± 02 of 4 0.84None
Whole fly3 ± 10 of 4



(CG30054):

Annotation Number : CG30054
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0050054
Gbrowse : chr2R:8511276-8512628 (+) // 100.0 //
Probeset : 1625303_at
Accessions : protein= NP_001036538;, nucleotide= NM_001043073;
Pathway : 0005834 // heterotrimeric G-protein complex // inferred from sequence or structural similarity
Interpro : 0000166 // nucleotide binding // inferred from electronic annotation /// 0004871 // signal transducer activity // inferr
FlyMine data for FBgn0050054.
Homophila reports that CG30054 is a close match (4e-61) to human gene AHO;GNAS;GNAS1;GPSA;PHP1A;PHP1B;POH (NP_001070956), a gene associated with Acromegaly, 102200 (3);McCune-Albright syndrome, 174800 (3);Osseous heteroplasia, progressive, 166350 (3);Pituitary ACTH secreting adenoma (3);Prolonged bleeding time, brachydac;Pseudohypoparathyroidism, type Ia, 103580 (3);Pseudohypoparathyroidism, type Ib, 603233 (3);Somatotrophinoma (3).
VDRC has 3 RNAi stocks for FBgn0050054 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain14 ± 04 of 4 8.20Up
Head3 ± 11 of 4 1.90None
Eye4 ± 11 of 4 2.81None
Thoracicoabdominal ganglion11 ± 14 of 4 6.60Up
Salivary gland6 ± 30 of 4 3.80None
Crop4 ± 00 of 4 2.30None
Midgut2 ± 10 of 4 1.60None
Tubule5 ± 01 of 4 3.20Up
Hindgut3 ± 10 of 4 2.10None
Heart1 ± 00 of 4 0.74None
Fat body13 ± 73 of 4 7.68None
Ovary1 ± 00 of 4 0.80None
Testis1 ± 00 of 4 1.00None
Male accessory glands11 ± 13 of 4 6.30Up
Virgin spermatheca4 ± 01 of 4 2.57Up
Mated spermatheca3 ± 00 of 4 2.12Up
Adult carcass4 ± 20 of 4 2.80None
Larval CNS7 ± 24 of 4 4.32Up
Larval Salivary gland5 ± 10 of 4 3.16None
Larval midgut1 ± 00 of 4 0.88None
Larval tubule4 ± 02 of 4 2.60Up
Larval hindgut4 ± 01 of 4 2.35Up
Larval fat body1 ± 00 of 4 0.70None
Larval trachea1 ± 20 of 4 0.97None
Larval carcass1 ± 00 of 4 0.86None
S2 cells (growing)2 ± 00 of 4 1.42None
Whole fly1 ± 00 of 4

Looking for FBgn0050054. 2 entries matched from 18771, in 1 s.


Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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