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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0086779 through 18771 annotations produced 1 hits

steppke (step):

Annotation Number : CG11628
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0086779
Gbrowse : chr2L:21741250-21757461 (-) // 100.0 //
Probeset : 1641368_at
Accessions : protein= NP_001036375; /// NP_001163041; /// NP_610120;, nucleotide= NM_001042910; /// NM_001169570; /// NM_136276;
Pathway : 0005622 // intracellular // inferred from electronic annotation
Interpro : 0005086 // ARF guanyl-nucleotide exchange factor activity // inferred from sequence or structural similarity /// 0005086
FlyMine data for FBgn0086779.
Homophila reports that CG11628 is a close match (1e-35) to human gene ARFGEF2;BIG2 (NP_006411), a gene associated with Periventricular heterotopia with microcephaly, 608097 (3).
BioGrid reports that CG11628 interacts with CG32684 CG11876 CG13458 CG15112 CG17358 CG3052 CG7171 CG8207 CG8232 CG9936 .
TRiP has 1 RNAi stocks for FBgn0086779 available for purchase.
VDRC has 1 RNAi stocks for FBgn0086779 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain110 34 of 4 0.50Down
Head74 84 of 4 0.40Down
Eye44 14 of 4 0.21Down
Thoracicoabdominal ganglion75 24 of 4 0.40Down
Salivary gland100 44 of 4 0.49Down
Crop110 44 of 4 0.50Down
Midgut45 04 of 4 0.20Down
Tubule47 24 of 4 0.20Down
Hindgut84 64 of 4 0.40Down
Heart51 24 of 4 0.25Down
Fat body48 84 of 4 0.24Down
Ovary439 74 of 4 2.10Up
Testis180 54 of 4 0.90None
Male accessory glands124 124 of 4 0.60Down
Virgin spermatheca42 44 of 4 0.21Down
Mated spermatheca47 34 of 4 0.23Down
Adult carcass79 24 of 4 0.40Down
Larval CNS69 24 of 4 0.34Down
Larval Salivary gland97 84 of 4 0.47Down
Larval midgut39 44 of 4 0.19Down
Larval tubule64 54 of 4 0.30Down
Larval hindgut42 34 of 4 0.21Down
Larval fat body112 64 of 4 0.50Down
Larval trachea75 104 of 4 0.37Down
Larval carcass45 84 of 4 0.22Down
S2 cells (growing)241 104 of 4 1.18None
Whole fly204 144 of 4

Looking for FBgn0086779. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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