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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0087039 through 18771 annotations produced 1 hits

SECIS-binding protein 2 (Sbp2):

Annotation Number : CG7066
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0087039
Gbrowse : chr3L:8297259-8298433 (+) // 100.0 //
Probeset : 1626543_at
Accessions : protein= NP_648204;, nucleotide= NM_139947;
FlyMine data for FBgn0087039.
Homophila reports that CG7066 is a close match (1e-17) to human gene SBP2;SECISBP2 (NP_076982), a gene associated with Thyroid hormone metabolism, abnormal, 609698 (3).
VDRC has 2 RNAi stocks for FBgn0087039 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain118 44 of 4 1.00None
Head91 54 of 4 0.70Down
Eye98 64 of 4 0.80Down
Thoracicoabdominal ganglion121 44 of 4 1.00None
Salivary gland81 73 of 4 0.67Down
Crop173 54 of 4 1.40Up
Midgut82 30 of 4 0.70Down
Tubule69 44 of 4 0.60Down
Hindgut89 64 of 4 0.70Down
Heart106 54 of 4 0.87None
Fat body99 64 of 4 0.81Down
Ovary219 54 of 4 1.80Up
Testis14 10 of 4 0.10Down
Male accessory glands126 44 of 4 1.00None
Virgin spermatheca176 54 of 4 1.44Up
Mated spermatheca175 114 of 4 1.44Up
Adult carcass103 54 of 4 0.80Down
Larval CNS157 34 of 4 1.29Up
Larval Salivary gland48 30 of 4 0.40Down
Larval midgut118 114 of 4 0.97None
Larval tubule125 84 of 4 1.00None
Larval hindgut99 74 of 4 0.81Down
Larval fat body161 164 of 4 1.30None
Larval trachea178 94 of 4 1.46Up
Larval carcass86 43 of 4 0.71Down
S2 cells (growing)129 34 of 4 1.06None
Whole fly122 44 of 4

Looking for FBgn0087039. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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