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FlyAtlas: the Drosophila gene expression atlas

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Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.


This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)


Searching for FBGN0260745 through 18771 annotations produced 1 hits



Midline Fasciclin (mfas):

Annotation Number : CG3359
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0260745
Gbrowse : chr3R:7810583-7819037 (-) // 100.0 //
Probeset : 1632298_s_at
Accessions : protein= NP_524324; /// NP_731661; /// NP_788643; /// NP_788644; /// NP_788645; /// NP_788646; /// NP_788647; /// NP_788648; /// NP_788649; /// NP_788650; /// NP_788651; /// NP_788652; /// NP_788653; /// NP_788654; /// NP_788655;, nucleotide= NM_079600; /// NM_169444; /// NM_176466; /// NM_176467; /// NM_176468; /// NM_176469; /// NM_176470; /// NM_176471; /// NM_176472; /// NM_176473; /// NM_176474; /// NM_176475; /// NM_176476; /// NM_176477; /// NM_176478;
Pathway : 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // non-traceable author statemen
FlyMine data for FBgn0260745.
Homophila reports that CG3359 is a close match (5e-24) to human gene BIGH3;CDG2;CDGG1;CSD;CSD2;EBMD;TGFBI (NP_000349), a gene associated with Corneal dystrophy, Avellino type, 607541 (3);Corneal dystrophy, epithelial basement membrane, 121820 (3);Corneal dystrophy, Groenouw type I, 121900 (3);Corneal dystrophy, lattice type I, 122200 (3);Corneal dystrophy, lattice type IIIA, 608471 (3);Corneal dystrophy, Reis-Bucklers type, 608470 (3);Corneal dystrophy, Thiel-Behnke type, 602082 (3).
VDRC has 3 RNAi stocks for FBgn0260745 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain1197 ± 414 of 4 3.30Up
Head733 ± 334 of 4 2.00Up
Eye265 ± 164 of 4 0.74Down
Thoracicoabdominal ganglion1603 ± 544 of 4 4.40Up
Salivary gland462 ± 774 of 4 1.28None
Crop426 ± 124 of 4 1.20Up
Midgut117 ± 84 of 4 0.30Down
Tubule16 ± 11 of 4 0.00Down
Hindgut1391 ± 504 of 4 3.90Up
Heart68 ± 94 of 4 0.19Down
Fat body40 ± 64 of 4 0.11Down
Ovary106 ± 184 of 4 0.30Down
Testis464 ± 234 of 4 1.30Up
Male accessory glands8659 ± 2324 of 424.00Up
Virgin spermatheca102 ± 54 of 4 0.29Down
Mated spermatheca135 ± 104 of 4 0.37Down
Adult carcass279 ± 114 of 4 0.80Down
Larval CNS214 ± 124 of 4 0.59Down
Larval Salivary gland329 ± 134 of 4 0.91None
Larval midgut113 ± 84 of 4 0.31Down
Larval tubule16 ± 34 of 4 0.00Down
Larval hindgut777 ± 504 of 4 2.16Up
Larval fat body418 ± 544 of 4 1.20None
Larval trachea4359 ± 2434 of 412.09Up
Larval carcass188 ± 114 of 4 0.52Down
S2 cells (growing)1246 ± 454 of 4 3.46Up
Whole fly360 ± 64 of 4

Looking for FBgn0260745. 1 entries matched from 18771, in 1 s.


Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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