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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0260945 through 18771 annotations produced 1 hits

Autophagy-specific gene 1 (Atg1):

Annotation Number : CG10967
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0260945
Gbrowse : chr3L:12778230-12798214 (-) // 100.0 //
Probeset : 1627886_at
Accessions : protein= NP_001163433; /// NP_648601;, nucleotide= NM_001169962; /// NM_140344;
Interpro : 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred
FlyMine data for FBgn0260945.
Homophila reports that CG10967 is a close match (5e-11) to human gene ERBB2;HER2;NEU;NGL (NP_004439), a gene associated with Adenocarcinoma of lung, somatic, 211980 (3);Gastric cancer, somatic, 137215 (3);Glioblastoma, somatic, 137800 (3);Ovarian cancer, somatic, (3).
BioGrid reports that CG10967 interacts with CG16719 CG8609 CG9046 CG15006 CG17508 CG5708 CG11182 CG17046 CG2944 CG14816 CG5731 CG31679 CG31811 CG7331 CG9930 CG8963 CG4184 CG32169 .
TRiP has 2 RNAi stocks for FBgn0260945 available for purchase.
VDRC has 1 RNAi stocks for FBgn0260945 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain770 104 of 4 3.90Up
Head340 94 of 4 1.70Up
Eye367 74 of 4 1.85Up
Thoracicoabdominal ganglion751 174 of 4 3.80Up
Salivary gland369 94 of 4 1.86Up
Crop308 114 of 4 1.60Up
Midgut247 64 of 4 1.20Up
Tubule274 454 of 4 1.40None
Hindgut202 64 of 4 1.00None
Heart282 24 of 4 1.42Up
Fat body531 234 of 4 2.68Up
Ovary326 84 of 4 1.60Up
Testis58 44 of 4 0.30Down
Male accessory glands104 34 of 4 0.50Down
Virgin spermatheca335 104 of 4 1.69Up
Mated spermatheca303 124 of 4 1.53Up
Adult carcass316 124 of 4 1.60Up
Larval CNS380 214 of 4 1.92Up
Larval Salivary gland221 84 of 4 1.12None
Larval midgut203 414 of 4 1.02None
Larval tubule444 504 of 4 2.20Up
Larval hindgut177 154 of 4 0.89None
Larval fat body443 1104 of 4 2.20None
Larval trachea161 194 of 4 0.81Down
Larval carcass188 334 of 4 0.95None
S2 cells (growing)201 84 of 4 1.01None
Whole fly198 104 of 4

Looking for FBgn0260945. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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