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FlyAtlas: the Drosophila gene expression atlas

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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.


This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)


Searching for FBGN0260959 through 18771 annotations produced 2 hits



Microcephalin (MCPH1):

Annotation Number : CG30038
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0260959
Gbrowse : chr2R:7783495-7784193 (-) // 100.0 //
Probeset : 1628629_at
Accessions : protein= NP_001163122; /// NP_001163123; /// NP_610711; /// NP_725088;, nucleotide= NM_001169651; /// NM_001169652; /// NM_136867; /// NM_165852;
Pathway : 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay
FlyMine data for FBgn0260959.
Homophila reports that CG30038 is a close match (2e-22) to human gene MCPH1 (NP_078872), a gene associated with Microcephaly, autosomal recessive 1, 251200 (3);Premature chromosome condensation with microcephaly and mental retardation, 606858 (3).
TRiP has 1 RNAi stocks for FBgn0260959 available for purchase.
VDRC has 5 RNAi stocks for FBgn0260959 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain13 ± 14 of 4 0.10Down
Head27 ± 24 of 4 0.10Down
Eye20 ± 14 of 4 0.10Down
Thoracicoabdominal ganglion18 ± 12 of 4 0.10Down
Salivary gland116 ± 84 of 4 0.56Down
Crop49 ± 44 of 4 0.20Down
Midgut68 ± 24 of 4 0.30Down
Tubule429 ± 424 of 4 2.10Up
Hindgut54 ± 34 of 4 0.30Down
Heart79 ± 14 of 4 0.39Down
Fat body82 ± 164 of 4 0.40Down
Ovary237 ± 54 of 4 1.10None
Testis1357 ± 344 of 4 6.50Up
Male accessory glands107 ± 44 of 4 0.50Down
Virgin spermatheca51 ± 34 of 4 0.25Down
Mated spermatheca54 ± 44 of 4 0.26Down
Adult carcass86 ± 84 of 4 0.40Down
Larval CNS71 ± 64 of 4 0.35Down
Larval Salivary gland125 ± 104 of 4 0.60Down
Larval midgut73 ± 64 of 4 0.35Down
Larval tubule200 ± 104 of 4 1.00None
Larval hindgut81 ± 44 of 4 0.39Down
Larval fat body163 ± 594 of 4 0.80None
Larval trachea84 ± 94 of 4 0.41Down
Larval carcass65 ± 94 of 4 0.32Down
S2 cells (growing)150 ± 24 of 4 0.72Down
Whole fly207 ± 124 of 4



Microcephalin (MCPH1):

Annotation Number : CG8981
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0260959
Gbrowse : chr2R:7784346-7791419 (-) // 100.0 //
Probeset : 1626590_a_at
Accessions : protein= NP_001163122; /// NP_001163123; /// NP_610711; /// NP_725088;, nucleotide= NM_001169651; /// NM_001169652; /// NM_136867; /// NM_165852;
Pathway : 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay
FlyMine data for FBgn0260959.
Homophila reports that CG8981 is a close match (2e-11) to human gene MCPH1 (NP_078872), a gene associated with Microcephaly, autosomal recessive 1, 251200 (3);Premature chromosome condensation with microcephaly and mental retardation, 606858 (3).
BioGrid reports that CG8981 interacts with CG9572 .
TRiP has 1 RNAi stocks for FBgn0260959 available for purchase.
VDRC has 5 RNAi stocks for FBgn0260959 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain4 ± 01 of 4 0.00Down
Head14 ± 03 of 4 0.10Down
Eye4 ± 21 of 4 0.04Down
Thoracicoabdominal ganglion6 ± 11 of 4 0.10Down
Salivary gland39 ± 34 of 4 0.33Down
Crop24 ± 24 of 4 0.20Down
Midgut32 ± 14 of 4 0.30Down
Tubule119 ± 194 of 4 1.00None
Hindgut20 ± 24 of 4 0.20Down
Heart12 ± 23 of 4 0.11Down
Fat body37 ± 54 of 4 0.31Down
Ovary203 ± 34 of 4 1.70Up
Testis202 ± 54 of 4 1.70Up
Male accessory glands25 ± 52 of 4 0.20Down
Virgin spermatheca12 ± 23 of 4 0.10Down
Mated spermatheca15 ± 32 of 4 0.13Down
Adult carcass40 ± 24 of 4 0.30Down
Larval CNS25 ± 34 of 4 0.22Down
Larval Salivary gland26 ± 42 of 4 0.23Down
Larval midgut29 ± 14 of 4 0.24Down
Larval tubule111 ± 64 of 4 0.90None
Larval hindgut29 ± 24 of 4 0.25Down
Larval fat body46 ± 124 of 4 0.40Down
Larval trachea16 ± 34 of 4 0.14Down
Larval carcass29 ± 44 of 4 0.24Down
S2 cells (growing)95 ± 74 of 4 0.80None
Whole fly118 ± 94 of 4

Looking for FBgn0260959. 2 entries matched from 18771, in 1 s.


Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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