FlyAtlas: the Drosophila gene expression atlas

Biotechnology & Biological Sciences Research Council

Home & Search

Batch/table Search

Tissues Search

BLASTP Search

About & FAQ

Top 50

Original data

Interesting meta-analysis

Links

Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

Searching for FBGN0261387 through 18771 annotations produced 1 hits

Protein kinase 1 (CG17528):

Annotation Number : CG17528
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0261387
Gbrowse : chr2R:704673-711821 (-) // 100.0 //
Probeset : 1630817_s_at
Accessions : protein= NP_001036461; /// NP_001036462; /// NP_001036463; /// NP_001036464;, nucleotide= NM_001042996; /// NM_001042997; /// NM_001042998; /// NM_001042999;
Pathway : 0005875 // microtubule associated complex // inferred from sequence or structural similarity
Interpro : 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred
FlyMine data for FBgn0261387.
Homophila reports that CG17528 is a close match (6e-11) to human gene ACH;FGFR3 (NP_075254), a gene associated with Achondroplasia, 100800 (3);Bladder cancer, 109800 (3);CATSHL syndrome, 610474 (3);Cervical cancer, somatic, 603956 (3);Colorectal cancer, somatic, 109800 (3);Crouzon syndrome with acanthosis nigricans, 612247 (3);Hypochondroplasia, 146000 (3);LADD syndrome, 149730 (3);Muenke syndrome, 602849 (3);Nevus, keratinocytic, nonepidermolytic, 162900 (3);Thanatophoric dysplasia, types I and II, 187600 (3).
BioGrid reports that CG17528 interacts with CG4167 .
TRiP has 2 RNAi stocks for FBgn0261387 available for purchase.

Tissue	mRNA Signal	Present Call	Enrichment	Affy Call
Brain	274 ± 1	4 of 4	1.40	Up
Head	139 ± 12	4 of 4	0.70	Down
Eye	136 ± 8	4 of 4	0.68	Down
Thoracicoabdominal ganglion	189 ± 10	4 of 4	0.90	None
Salivary gland	159 ± 9	4 of 4	0.80	Down
Crop	133 ± 3	4 of 4	0.70	Down
Midgut	105 ± 6	4 of 4	0.50	Down
Tubule	134 ± 6	4 of 4	0.70	Down
Hindgut	125 ± 2	4 of 4	0.60	Down
Heart	66 ± 4	4 of 4	0.33	Down
Fat body	76 ± 6	4 of 4	0.38	Down
Ovary	404 ± 10	4 of 4	2.00	Up
Testis	172 ± 3	4 of 4	0.90	None
Male accessory glands	122 ± 2	4 of 4	0.60	Down
Virgin spermatheca	62 ± 1	4 of 4	0.31	Down
Mated spermatheca	66 ± 5	4 of 4	0.33	Down
Adult carcass	100 ± 4	4 of 4	0.50	Down
Larval CNS	272 ± 13	4 of 4	1.36	Up
Larval Salivary gland	149 ± 11	4 of 4	0.74	Down
Larval midgut	86 ± 4	4 of 4	0.43	Down
Larval tubule	137 ± 3	4 of 4	0.70	Down
Larval hindgut	112 ± 4	4 of 4	0.56	Down
Larval fat body	108 ± 3	4 of 4	0.50	Down
Larval trachea	130 ± 6	4 of 4	0.65	Down
Larval carcass	112 ± 10	4 of 4	0.56	Down
S2 cells (growing)	226 ± 6	4 of 4	1.13	None
Whole fly	200 ± 11	4 of 4

Looking for FBgn0261387. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720