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FlyAtlas: the Drosophila gene expression atlas

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Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.


This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)


Searching for FBGN0261530 through 18771 annotations produced 1 hits



():

Annotation Number : CG6754
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0261530
Gbrowse : chr3L:9713511-9716548 (-) // 100.0 //
Probeset : 1632161_at
Accessions : protein= NP_651973;, nucleotide= NM_143716;
Pathway : signal transduction resulting in induction of apoptosis // inferred from mutant phenotype /// 0016233 // telomere cappi
Interpro : 0005622 // intracellular // inferred from electronic annotation
FlyMine data for FBgn0261530.
Homophila reports that CG6754 is a close match (2e-22) to human gene NBS;NBS1 (NP_001019859), a gene associated with Leukemia, acute lymphoblastic (3);Nijmegen breakage syndrome, 251260 (3).
BioGrid reports that CG6754 interacts with CG7241 CG12428 CG31634 CG4994 .
VDRC has 3 RNAi stocks for FBgn0261530 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain121 ± 24 of 4 1.20Up
Head58 ± 34 of 4 0.60Down
Eye65 ± 34 of 4 0.64Down
Thoracicoabdominal ganglion120 ± 64 of 4 1.20None
Salivary gland41 ± 54 of 4 0.41Down
Crop66 ± 24 of 4 0.70Down
Midgut34 ± 14 of 4 0.30Down
Tubule38 ± 14 of 4 0.40Down
Hindgut68 ± 34 of 4 0.70Down
Heart31 ± 04 of 4 0.31Down
Fat body24 ± 24 of 4 0.24Down
Ovary269 ± 74 of 4 2.70Up
Testis171 ± 74 of 4 1.70Up
Male accessory glands82 ± 34 of 4 0.80Down
Virgin spermatheca38 ± 14 of 4 0.38Down
Mated spermatheca36 ± 44 of 4 0.36Down
Adult carcass36 ± 34 of 4 0.40Down
Larval CNS83 ± 54 of 4 0.82Down
Larval Salivary gland37 ± 34 of 4 0.37Down
Larval midgut22 ± 24 of 4 0.22Down
Larval tubule51 ± 24 of 4 0.50Down
Larval hindgut53 ± 34 of 4 0.52Down
Larval fat body45 ± 54 of 4 0.50Down
Larval trachea65 ± 74 of 4 0.65Down
Larval carcass29 ± 54 of 4 0.29Down
S2 cells (growing)132 ± 44 of 4 1.31Up
Whole fly101 ± 44 of 4

Looking for FBgn0261530. 1 entries matched from 18771, in 1 s.


Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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