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FlyAtlas: the Drosophila gene expression atlas

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Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.


This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)


Searching for FBGN0261930 through 18771 annotations produced 2 hits



():

Annotation Number : HDC16822
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0003986
Gbrowse : chrX:476991-478434 (+) // 100.0 //
Probeset : 1638759_at
Accessions : protein= NP_001036253; /// NP_476786;, nucleotide= NM_001042788; /// NM_057438;
Pathway : DNA-dependent // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred fr
Interpro : 0005634 // nucleus // inferred from electronic annotation
FlyMine data for FBgn0003986.
VDRC has 2 RNAi stocks for FBgn0003986 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain1 ± 00 of 4 0.40Down
Head1 ± 10 of 4 0.50None
Eye2 ± 10 of 4 0.83None
Thoracicoabdominal ganglion1 ± 10 of 4 0.60None
Salivary gland6 ± 20 of 4 1.84None
Crop4 ± 11 of 4 1.40None
Midgut15 ± 24 of 4 4.70Up
Tubule1 ± 00 of 4 0.60Down
Hindgut1 ± 00 of 4 0.40None
Heart1 ± 00 of 4 0.61None
Fat body1 ± 20 of 4 0.53None
Ovary0 ± 00 of 4 0.30Down
Testis0 ± 00 of 4 0.30Down
Male accessory glands3 ± 10 of 4 1.10None
Virgin spermatheca2 ± 10 of 4 0.71None
Mated spermatheca2 ± 10 of 4 0.68None
Adult carcass0 ± 00 of 4 0.20Down
Larval CNS0 ± 00 of 4 0.22Down
Larval Salivary gland3 ± 10 of 4 1.03None
Larval midgut4 ± 10 of 4 1.53None
Larval tubule0 ± 00 of 4 0.10Down
Larval hindgut2 ± 10 of 4 0.89None
Larval fat body2 ± 10 of 4 0.80None
Larval trachea0 ± 10 of 4 0.25Down
Larval carcass1 ± 00 of 4 0.49None
S2 cells (growing)0 ± 00 of 4 0.30Down
Whole fly3 ± 00 of 4



chrX:485074-491855 (+) // 100.0 // ():

Annotation Number : CG6172
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : full length
Gbrowse : March 2006 (FlyBase/BDGP 5.3)
Probeset : 1635383_at
Accessions : protein= , nucleotide= NP_001036253; /// NP_476786;
Pathway : "0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription
Interpro : DNA-dependent // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred fr
FlyMine data for full length.
Homophila reports that CG6172 is a close match (4e-11) to human gene CRS2;HOX8;MSX2 (NP_002440), a gene associated with Craniosynostosis, type 2, 604757 (3);Parietal foramina 1, 168500 (3);Parietal foramina with cleidocranial dysplasia, 168550 (3).
BioGrid reports that CG6172 interacts with CG7010 CG7054 CG7823 CG9745 .


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain6 ± 00 of 4 0.30Down
Head4 ± 11 of 4 0.20Down
Eye3 ± 10 of 4 0.16Down
Thoracicoabdominal ganglion10 ± 21 of 4 0.50Down
Salivary gland18 ± 70 of 4 0.81None
Crop2 ± 00 of 4 0.10Down
Midgut289 ± 134 of 413.00Up
Tubule5 ± 00 of 4 0.20Down
Hindgut6 ± 11 of 4 0.30Down
Heart1 ± 00 of 4 0.08Down
Fat body12 ± 42 of 4 0.54None
Ovary3 ± 00 of 4 0.20Down
Testis2 ± 00 of 4 0.10Down
Male accessory glands8 ± 20 of 4 0.40Down
Virgin spermatheca8 ± 10 of 4 0.37Down
Mated spermatheca7 ± 10 of 4 0.35Down
Adult carcass8 ± 30 of 4 0.40Down
Larval CNS17 ± 44 of 4 0.80None
Larval Salivary gland11 ± 21 of 4 0.51Down
Larval midgut104 ± 124 of 4 4.68Up
Larval tubule3 ± 20 of 4 0.10Down
Larval hindgut5 ± 10 of 4 0.24Down
Larval fat body12 ± 10 of 4 0.60Down
Larval trachea1 ± 00 of 4 0.05Down
Larval carcass6 ± 00 of 4 0.28Down
S2 cells (growing)7 ± 10 of 4 0.36Down
Whole fly22 ± 34 of 4

Looking for FBgn0261930. 2 entries matched from 18771, in 1 s.


Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

measure downtime