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FlyAtlas: the Drosophila gene expression atlas

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Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.


This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)


Searching for FBGN0262476 through 18771 annotations produced 1 hits



():

Annotation Number : CG5226
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0034355 /// FBgn0260236
Gbrowse : chr2R:14402080-14412926 (+) // 99.68 //
Probeset : 1634512_at
Accessions : protein= NP_001163195; /// NP_611340;, nucleotide= NM_001169724; /// NM_137496;
Pathway : 0005887 // integral to plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from e
Interpro : 0005328 // neurotransmitter:sodium symporter activity // inferred from electronic annotation /// 0015293 // symporter ac
FlyMine data for FBgn0034355 /// FBgn0260236.
Homophila reports that CG5226 is a close match (4e-63) to human gene DAT1;SLC6A3 (NP_001035), a gene associated with {Attention-deficit hyperactivity disorder, susceptibility to}, 143465 (2);{Major affective disorder}, 125480 (3);{Nicotine dependence, protection against}, 188890 (3).


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain1037 124 of 414.60Up
Head233 44 of 4 3.30Up
Eye105 64 of 4 1.48Up
Thoracicoabdominal ganglion1107 264 of 415.60Up
Salivary gland18 12 of 4 0.26Down
Crop85 54 of 4 1.20None
Midgut31 24 of 4 0.40Down
Tubule13 03 of 4 0.20Down
Hindgut54 44 of 4 0.80Down
Heart63 114 of 4 0.89None
Fat body124 334 of 4 1.75Up
Ovary47 34 of 4 0.70Down
Testis21 14 of 4 0.30Down
Male accessory glands29 14 of 4 0.40Down
Virgin spermatheca15 04 of 4 0.21Down
Mated spermatheca19 34 of 4 0.27Down
Adult carcass136 254 of 4 1.90None
Larval CNS388 554 of 4 5.47Up
Larval Salivary gland9 14 of 4 0.13Down
Larval midgut11 14 of 4 0.16Down
Larval tubule7 04 of 4 0.10Down
Larval hindgut12 14 of 4 0.17Down
Larval fat body5 01 of 4 0.10Down
Larval trachea4 42 of 4 0.07Down
Larval carcass7 03 of 4 0.11Down
S2 cells (growing)2 12 of 4 0.03Down
Whole fly71 34 of 4

Looking for FBgn0262476. 1 entries matched from 18771, in 2 s.


Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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